Pulmonary eosinophilia associated with carbamazepine.

Extensive carbamazepine eruption with eosinophilia and pulmonary infiltrate.

Glandular fever-like syndrome, pulmonary eosinophilia and asthma associated with carbamazepine.

Introduction Carbamazepine is an important drug in the treatment of epilepsy in childhood. A number of side effects have been reported including extrapyramidal symptoms, lethargy, psychoses, skin eruptions and less commonly blood dyscrasias and liver damage (Gayford and Redpath, 1969). Drug-induced lung disease has been described in association with a number of drugs most notably nitrofurantoin...

Tropical Pulmonary Eosinophilia with Eosinophilic Leukemoid Reaction

A 7 year-old male presented with recurrent fever, cough and respiratory distress for over last 2 years. Based on extremely high eosinophil count, high Immunoglobulin E, increase in eosinophilic precursors in bone marrow, and positive antigen test for Wuchereria bancrofti, a diagnosis of Tropical Pulmonary Eosinophilia with Eosinophilic Leukemoid Reaction was made. Complete recovery was achieved...

Drug Hypersensitivity to Previously Tolerated Phenytoin by Carbamazepine-induced DRESS Syndrome

Drug rash with eosinophilia and systemic symptoms (DRESS) syndrome associated with anticonvulsant drugs is a rare but potentially life-threatening disease that occurs in response to arene oxide producing anticonvulsant such as phenytoin and carbamazepine. There have been many reports of cross reactivity among the anticonvulsants upon first exposure to the offending drugs. However, there has bee...

Eosinophilic leukemoid reaction associated with carbamazepine hypersensitivity.

Carbamazepine is widely used in the treatment of epilepsy, neuralgic pain, and bipolar affective disorders. Several adverse drug reactions have been described during the course of carbamazepine administration, including exanthemata and hematological reactions. Carbamazepine is one of the common drugs that have been implicated in the etiology of drug hypersensitivity syndrome. A 50-year-old male...